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It is characterized by immune signaling that does not appropriately turn off, contributing to multi-system symptoms such as fatigue, cognitive dysfunction, sleep disruption, temperature dysregulation, and heightened sensitivity to triggers

doi: 10.1016/j.cell.2017.11.034 181 XuYChenYZhangXMaJLiuYCuiLet al

If the specimen is suspicious, reaspiration or resection is mandatory

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